Answer Posted / dev rawat

In Toc Analyzer Calibration (System suitability) we are preparing Standard sucrose of 500PPb and Benzoquinone Preparing of 500ppb . Sucrose is easy to oxidized and p- Benzoquinone is hard to decompose(oxidized).Its molecule bound not easy to oxidized so the response efficiency defined in USP (united state pharmacopoeia )its response efficiency not less then 85% and not more then 115% . BQ run as control sample in the References of Sucrose .And Its Calculation methods [(rss-rw ) / (rs-rw)]100.

How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2390

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in gas chromatography what is the difference between gas flow rate and average linear velocity ?

2605

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1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.

2889

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how to decide for one product require water content or LOD?

786

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some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2656

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What is similarity factor?

1209

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can i use hplc detector to uplc and why?

2293

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Why use only methanol,used determinationof moisture content not use other solvents

1414

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in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

842

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what is the difference between potentiometric titration and karl fischer titration?

3194

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Why perchloric acid used for potentiometric titration

2684

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If vendor having more imp than monograph then how to proceed? and how to set spec?

935

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What is rs test why we are performing rs test?

1865

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what is mean by nitrosamine impurities?

1069

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In which situation we require to prepare the standard solution from sample in Related substance method?

781

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