Answer Posted / samresh pal

pH Play the role for ionisation and unionisation of drug molucule in mobile phase..if our drug moity is acidic nature and our mobile phase pH is acidic then our drug moity behave to unionised and unionised molecule behave like hydrophobic or nonpolar so drug moiety more attract to stationary phase( coloum) so it not eluted with mobile phase readily and mor time expend in coloum.

how require to set assay concentration for standard and sample?

922

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What is a difference between potency and purity?

1221

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in dissolution why pool sample needed? in which type of drug pool sample need?

3179

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Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

2865

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If combination product how require to identify which imp is of which api?

839

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We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?

1719

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CAN WE DETERMINE THE PEAK PURITY IN GAS CHROMATOGRAPHY ANALYSIS?

1209

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Did anybody have method for acetyl cysteine effervescnce tablet

2254

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Loss of linearity in tkn analysis, possible reasons?

1319

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If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

773

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What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

2038

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how the compound separate in coulunm,explain

2533

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if identification threshold crosses the limits then what next step?

864

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if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

681

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in hplc chromatogram started from left to right and in uv spectrum started from left to right

953

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