Answer Posted / pratibha

Because acetone react with methanol and forms water as a side reaction so no end point we get. so for Acetone pyridine or other base we use.

In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

3221

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How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2359

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1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1900

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In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )

3550

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if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

1042

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How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2628

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What is intact assay method development.....?

2754

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what is mean by extactable and leachable study?

1223

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What is shaking level in GC?

833

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What is Band broading effect explain

1938

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how many types of balance calibration test?

2353

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How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2436

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What is aggregate and fragments in SEC?

2155

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inhouse product is in capsule form in combination and RLD is in tablet form then can we proceed for multimedia CDP? in inhouse capsule product disso is paddle with sinker in release media is there then RLD product in tablet form then with same as paddle with sinker we can proceed n.a.?

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What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

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