Why methanol & acetonitrile is mostly used for hplc analysis?
Answer Posted / enochprasad
Drug substance/product easily dissolve in it.
Lower absorbance.
these solvents have lower wavelengths,whish compounds below 210nm these may helps to elute first from the column.As a results it will not effect pressure on the column
Is This Answer Correct ? | 2 Yes | 3 No |
Post New Answer View All Answers
how to decide for one product require water content or LOD?
in dissolution why pool sample needed? in which type of drug pool sample need?
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
what is diffrence between specificity and selecivity?
i want model written test paper for the post of analyst in IOCL(indian oil corporation ltd) any one pls help me
Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?
how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,
Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?
A ha tc is actual defination of retention time?
Why we use potassium dichromate in uv calibration Exact reason behind it??
Why potassium dichromate is used in calibration of uv?
How will u perform degradation study in detectors other thann PDA in HPLC Methodology
What is the purpose of octyl silane columns?
IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?
Did anybody have method for acetyl cysteine effervescnce tablet