how do you established the RRF for unknown impurity
- 6 Answers
- 11394 Views
- Square Pharma, I also Faced
- E-Mail Answers
Answer Posted / anjaneyulu
First we find response factor
response factor of impurity
=concentration of sample/area of impurity
RRF for unknown impurity is
=response factor of impurity/area of main peak.
| Is This Answer Correct ? | 3 Yes | 2 No |
Post New Answer View All Answers
If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?
[3/30, 13:29] Manoj P Venkatpurwar: How hplc column selection according to structure? How mobile phase buffer selection on molecule structure?
for which product require to do content uniformity? what is limit of cu?
how many types of balance calibration test?
In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?
how we can identify the impurity is coming below loq at transfering site?
Tell me about analytical method validation in QC
Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
In rs method development when we are going area normalization method to dilute standard method?
For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?
What is diffrence between extractable volume and deliverable volume? Answer pls
In which situation we require to prepare the standard solution from sample in Related substance method?
which are the diffrent batches in the pharmaceuticals?
What is intact assay method development.....?
