Answer Posted / naveen

In LC:
5 replicates of standard if %rsd is 2.0% orless
6 replicates of standard if %rsd is more than 2.0%

How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2363

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identification is for unknown? qualification for known? reporting for LOQ?

780

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What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8921

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What is the acceptance criteria for moisture balance when calibrated with sodium sulfate

2093

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2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

2267

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How do we fix the sample concentaryion in hplc method development?

1187

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What is aggregate and fragments in SEC?

2161

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if you get peak in blank then what require to do?

1026

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can i use hplc detector to uplc and why?

2354

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If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

1046

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What is the diference between residual solvents and organic volatile matter

2114

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How can I develope method of dissolution by HPLC OR UV

2457

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AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?

2116

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Why do we use KMnO4 in the test of control of obsorbance ? and why do we take specific quantity i.e 57-63mg?

2894

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Which is the highly polar and highly non polar column in HPLC?

2352

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