Interested to Buy Any Domain ? << Click Here >> for more details...
why
we
have
to
use
only
900
ml
buffer
in
dissolution
apparatus ?
what
are
the
conditions
that
favours
the
selection
of
volume
of
buffer?
- 1 Answers
- 7171 Views
- I also Faced
- E-Mail Answers
Answer Posted / t reddy
selecting volume of buffer depends upon the sink condition of the drug...
example: if ur drug maximum doasge is 500mg means.. take 3times of these dosage that is 1500mg... dissolve it 500ml buffer, there should not be any formation of precipitation in buffer... if there is any prcptn means increase the buffer volume until the drug getting completely dissolved... that will be the final volume for ur dissolution studies.
there is also another way 1st know the maximum solubility of dosage
example:if 500mg(consider this as 100%) in 900ml of buffer is the maximum solubility of the drug... then your doasge should not be more than 350mg(70%) in 900ml of buffer. u can use any dosage form less than 350mg for 900ml of buffer
| Is This Answer Correct ? | 6 Yes | 0 No |
Post New Answer View All Answers
Can any one tell me that which brand hplc column is used for levetiracetam imp- b test.
how to calculate potency of working standard by using mass balence method & this calculated potency is on as basis or on anhydrous/ dried basis
difference between RF and correction factor?
from hplc chromatogram how can we say that calibration is needed now?
what is the leak test procedure of filled bottles (liquid)
Give an example of how you've handled a problem patient.
why didn't you go back to previous employer after shifting to bangalore?
What r the different sop in or plant
What are your intentions towards the uplift of the hospital.
what is ur strengths and weekness in ur professional life as medical rep?
Tell us about a time when you failed to meet a deadline. What were the repercussions?
please e-mail me the model of Tamil Nadu drug inspector question papers
pls send me last two years solved papers of health & malaria inspector to kumar.santosh087@yahoo.com
when we connect the capacitor banks in series with the circuit? 2 144 pH is having unit?
while formulation of Gliclazide floating tablets why we are using direct cmpression technique why not wet granulation and what happend with that
