Dear Sir,
This is Thirunavukkarasu am working in Ordain Health Care
AR&D, Am Having one problem While doing method development
my question Metadoxine and Pyridoxine same chemical nature
and structural activity i tried lot of methods but Analyte
eluted same Retantion time i cant separate both peaks.
solubility, pH both are same only only difference melting
point metadoxine 210 C Pyridoxine 102 C please do the help
needful for me
Answer Posted / manoj kumar vadlamudi, ashla
Dear SIR,
Kindly play with different pH also...
and also try with RID detector....
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
which are the sizes of capsules?
HI,I CLEARED BOB CLERK EXAM. MY INTERVIEW WILL BE ON 9TH OCTOBER,2010.PLEASE SEND ME INTERVIEW QUESTIONS AND ANSWERS. THANK YOU.
What is the calibration of uv process and preparation
How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample
What is the difference between purge septum flow and column flow in gas chromatography?
How we can identify process related and degradation impurity in single method with short period?
what is classification of elemental impurities? what is risk assement in elemental impurities?
if you get peak in blank then what require to do?
in gas chromatography what is the difference between gas flow rate and average linear velocity ?
when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.
Difference between hlaf and rlaf
We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?
How doing qbd practically?
From where require to take the RLD sample?
What is similarity factor?