Dear Sir,
This is Thirunavukkarasu am working in Ordain Health Care
AR&D, Am Having one problem While doing method development
my question Metadoxine and Pyridoxine same chemical nature
and structural activity i tried lot of methods but Analyte
eluted same Retantion time i cant separate both peaks.
solubility, pH both are same only only difference melting
point metadoxine 210 C Pyridoxine 102 C please do the help
needful for me
Answer Posted / guest
its better to used ELSD detetor for the analysis
| Is This Answer Correct ? | 0 Yes | 1 No |
Post New Answer View All Answers
if you have given a blank water how you analyse by general analytical techniques?
how to calculate elemental impurities?
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
how require to fix the linearity and accuracy cincentration range?
if you have given one product then how you determine the impurity in that?
if you given one product then which tests you will perform?
what is mean by 40 in the dissolution basket mesh size?
how many types of balance calibration test?
what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?
Why we check moisture,ash & AIA in product
1)What's the meaning of Absorption,give a example. 2)What's the meaning of Adsorption,give a example. 2)what is the difference between Absorption and Adsorption.
why we are using benzene, anyline in acetic anhdride assay titration method?
How to do regeneration of Metacarb Pb plus column?
calibrtion procedue of LC-MS
If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?