Answer Posted / chandra bhushan tiwari

Calibration is done by known device (standard)againt the
the unknown device, it means instrument are working
properly or not and can be adjusted within tolerance.


Validation is to ensure the method which is to be used for
its intended purpose or not.

what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1921

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how the compound separate in coulunm,explain

2443

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some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2597

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what is mean by extactable and leachable study?

1097

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How to calculation of residual solvent methanol (3000 ppm) standard solution, and how many quantity used of test sample

3163

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We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy

1831

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what are risk assement in the analytical qbd?

685

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How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2338

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we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1801

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Loss of linearity in tkn analysis, possible reasons?

1253

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in which situation require to use paddle and basket?

669

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WHY pKa value is more important than pH value of the mobile phase in HPLC?

1710

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why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1642

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what is mean by peak intigrity?

861

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Why a1% value is used for some product ? What is the criteria for selection a1% value ?

2288

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