Interested to Buy Any Domain ? << Click Here >> for more details...
Answer Posted / kishor solanke (alkem)
To check the area(response) of analylite in the sample is
linear with respect to it's concentration OR injection
volume.This parameter done by two method:
1) Detector linearity:
In this linearity test the solution of different
concentration (linear conc.)are injected in triplicate of
each solution & linearity of each concentration calculated
as co-relation coefficient by graphical pattern in excle
against mean srea obtained.
2)Injector Linearity:
In this test the soluiton of same concentration injected in
triplicate with different injection (linear)volumes &
linearity calculated as above.
| Is This Answer Correct ? | 20 Yes | 0 No |
Post New Answer View All Answers
Why we use potassium dichromate in uv calibration Exact reason behind it??
why require to do water content for drug product?
if identification threshold crosses the limits then what next step?
what is partion and column chromatography
what is mean by covalidation
in hplc chromatogram started from left to right and in uv spectrum started from left to right
for which product require to do content uniformity? what is limit of cu?
in api coa contains only process impurities and in product coa contains degradation impurities?
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
what is classification of elemental impurities? what is risk assement in elemental impurities?
why octanol used to determine the partition coefficient ?
in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?
Why perchloric acid used for potentiometric titration
Which parameter require to do for analytical method equivalency?
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
