Answer Posted / manjeera

Elution of the compound depends on the type of chromatography whether it is reverse phase or normal phase chromatography.in reverse phase mobile phase will be polar so polar compound elutes first and vice versa for normal phase chromatography.

in which situation require to use paddle and basket?

794

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in which situation require to change rs specification?

796

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if peak get problamatic then what require to do?

861

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For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?

1964

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in each media we require to use SLS? how to proceed?

842

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Why are use silicon oil mr?

1257

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how many types of balance calibration test?

2355

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For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

2356

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when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

2096

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what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

3750

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How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2359

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in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?

786

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What is third generation HPLC Columns?

2035

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What is the principle of Thermal conductivity detector and FID?

2778

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IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?

2506

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