Answer Posted / urmila pawar

bcoz acetone has carbonyl functional grp which reacts with
metanol and forms different compound

how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

2286

---

How can we calculate offset value pH measurment

1502

---

some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?

2648

---

what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

886

---

What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

2676

---

in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?

717

---

Basic principle of ESI?

2142

---

what is the purge flow & how to calculate

2638

---

Why six unit used for precision?

1339

---

if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?

675

---

Tell me about analytical method validation in QC

6171

---

In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?

1967

---

How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?

3860

---

For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?

2308

---

How would you decide dissolution medium for NCE compound of class I drug

2248

---