If compound Pka is 5 then which buffer you will select ?

Answer Posted / sandip ankolia

u can not say that if Pka is 5 so use buffer near about pka
5 but depends upon the nature of compound , drift and noise.
genrally u can selet pH +/- 1.5 unit of the Pka value of
the compound.
Most important thing is that its not react with buffer,

Is This Answer Correct ?    5 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Basic principle of ESI?

1749


what is classification of elemental impurities? what is risk assement in elemental impurities?

428


how you establish the LOQ?

396


if you have given one product then how you determine the impurity in that?

382


how many types of balance calibration test?

1817






Which is the highly polar and highly non polar column in HPLC?

1898


what is mean by dissolution biowaiver study?

419


what is difference in ods I ods II is this is realy from sorbent / packing characteristics or from other means

1586


what is third integration

1588


Difference between the quantitative analysis and qualitative analysis?

725


For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?

3600


why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?

9125


How doing qbd practically?

528


If vendor having more imp than monograph then how to proceed? and how to set spec?

442


in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

457