When we calculate Impurity against impurity std.solution
and when we calculate impurity against diluted standard with
applying RRF?
Answer Posted / mukesh patel
impurity can be calculated against impurity when impurity
availability is sufficient.and easily available for routine
analysis and there is huge difference in RF or RRF with
main analylte.impurity can be calculated against diluted
standard with applying RRF when peak get saturated in
sample solution.
| Is This Answer Correct ? | 14 Yes | 0 No |
Post New Answer View All Answers
what is mean by dissolution hydrodynamics?
What is third generation HPLC Columns?
what is definition of validation? which components are followed give detail?
how can give the expiry period and restadardisation of volumetric solution
on the basis of bcs class how to proceed the solubility?
What is shaking level in GC?
before starting analytical method valodation what you checking? and how giving preference to start validation?
How we choose the mobile phase for method development.?
Why only hydroxy naphthol blue indicator is used for standardisation of 0.05M EDTA solution instead of solochrome Black T or Euriochrome Black T indicator which is used for all sample analysis with 0.05M EDTA solution?
what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.
what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?
What is the difference between purge septum flow and column flow in gas chromatography?
why octanol used to determine the partition coefficient ?
What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)
How to fix the sample conc. in Related substances test by HPLC?