Interested to Buy Any Domain ? << Click Here >> for more details...
WHAT IS DIFFERENCE BETWEEN RRT AND RRF IN HPLC
- 2 Answers
- 50510 Views
- Cadila, I also Faced
- E-Mail Answers
Answer Posted / naresh t
Relative retention time (RRT) is used to know where peaks apart from main compound elutes in HPLC analysis.
Where as Relative Response factor (RRF) comes into picture when our compound and impurities have different wavelength maxima. In this case impurities show either higher or lower response when the analysis is performed at wavelength maxima of main peak. So in quantification analysis the values obtained for impurities are not the actual values. In order to calculate the actual value of impurities' a correction factor is applies. this factor is called RRF
| Is This Answer Correct ? | 84 Yes | 6 No |
Post New Answer View All Answers
what type of question will ask in the interview of lab chemist.
Why we check moisture,ash & AIA in product
Qc interview questions
What is stray light in uv what are units for stray light
Why Ethanol is Used for Standardization of GC Head space?
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
What if impurity area in control sample coming more as compared to LOQ level of impurity ?
Why a1% value is used for some product ? What is the criteria for selection a1% value ?
why we use glass fiber filters use in some situation?
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?
Why only Copper standard is used to calibrate Atomic Absorption spectrophotometer?
Which parameters require to do in tech transfer?
why require to do water content for drug product?
cefoperozone and sulbactam inj. hplc test method
