Answer Posted / ganesh bhavar

for endcapping in reversed phase column use Trimethylamine
means it protect the OH-group silanol group

What is the principle of HPLC, GC, LCMS, GCMS,LC QQQ, GC QQQ, LC Q TOF and GC Q TOF. What are the applications and Specificity?

8916

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In GC calibration,what is the procedure to calibrate the TCD (thermal counductivity detector)suggest ?

3222

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in api coa contains only process impurities and in product coa contains degradation impurities?

733

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How doing qbd practically?

1032

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How to set specification of assay, fisdolution and related substances?

931

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why does used dry caffien in HPLC calibration?

2076

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what is lod and loq ?,why use k2cr2o7 , kcl h2so4 in uv calibration ?,why use benzophenone & caffene acetone in hplc calibration ?,what is leading peak in hplc ?why we do the calibration of limit of stry light in hplc & uv ?

3723

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For limit test of heavy metals in BP, Method C require that the substance is ignited at a temperature not exceeding 800 °C. Why confines such the temperature?

4131

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process of Diclofenac sodium,IP.

2284

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How require to perform linearity as per ANVISA? What are the acceptance criteria?

1399

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Why a1% value is used for some product ? What is the criteria for selection a1% value ?

2393

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if identification threshold crosses the limits then what next step?

915

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how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,

2649

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How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2436

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Which parameters require to do in tech transfer?

817

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