in what basis wavelength will select for a compound at
initial method development trials
Answer Posted / ramkrishna thakare
1 ) for any unknown compound firstly solubility check.
2 ) then on the basis of solubility UV - scanning should
be done
3 ) on the basis of UV - scanning Maxima must be
checked.& then on the basis MAXIMA wavelength should be
selected.it may multiwavelength or single-wavelength maxima .
RAMKRISHNA THAKARE -------SANDOZ
Is This Answer Correct ? | 29 Yes | 1 No |
Post New Answer View All Answers
what is %labelled amount in content uniformity of dosage unit and its calculation?
As per ICH related substances stability trend limit from initial to shelf life
How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.
in monograph 7 imp are there but in vendor showing 5 imp do not req to include 2 imp for that what will be justification?
what type of question will ask in the interview of lab chemist.
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
how to set sample and standard concentration in RS method?
Why potassium dichromate is used in calibration of uv?
How do we fix the sample concentaryion in hplc method development. What is the basis?
if you given one product then which tests you will perform?
If vendor having more imp than monograph then how to proceed? and how to set spec?
what is the origin to prepare standard operating procedure
how to selecet an exact coloumn for an new molecule development by hplc how to select exact salt as buffer for new molecule development by hplc what is the the process to select the mode of saparation of compoundes by hplc what is the use of ph of buffer what is use of buffer,ph,organic phase,ans methods how the molecules get saparated in coloumn,
why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space
If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?