Answer Posted / tschavda1985

ANALYTICAL CHEMISTRY

what are risk assement in the analytical qbd?

739

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what is the purge flow & how to calculate

2635

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what is third integration

1965

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

847

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Why we use potassium dichromate in uv calibration Exact reason behind it??

1249

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for which product require to do content uniformity? what is limit of cu?

806

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why we use glass fiber filters use in some situation?

784

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when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

2035

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How will u perform degradation study in detectors other thann PDA in HPLC Methodology

2535

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How to compare XRD graphs against standard and carry polymorpism study of API's by powder XRD method?

3858

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In the isomers,enantiomers give the only physical properties present such that no chemical properties present.

2214

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effect of pore size, pore volume, partical size, column length, carbon load on retention time? what is carbon load? what is the use?

912

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How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

2300

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How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2381

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in api coa contains only process impurities and in product coa contains degradation impurities?

694

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