Answer Posted / prerna

Gradient Programme for port A and C :
00 : 100
00 : 100
25 : 75
25 : 75
50 : 50
50 : 50
75 : 25
75 : 25
100 : 00
100 : 00

Above programme also run for port B and D

An increasing stepwise piramid will appear. Integrate that
peak and also split each step of the peak.

Find out its height and area of height

By using the formula ( which I don't remeber ), mean flow
of solvent at each step.
Flow : Limit
25 (24-26)
50 (49-51)
75 (74-76)
100 (100)

If the observed value is within the acceptance limit then
that pump passes the test.

in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?

886

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on the basis of bcs class how to proceed the solubility?

830

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Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.

2911

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How to know the estimated LOQ concentration in ppm

1276

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how decide the clining method and cleaning method validation require for this perticular products?

817

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My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards

1652

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in which situation ion pair agent require to use?

799

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if instrument calibration fails then what require to do?

1017

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If inhouse hplc related substance method is completly diffrent from Usp for finished proďuct with diffrent impurities then how require to prove method equivalecy?

816

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If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately

906

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Home heating oil or furnace oil what is made from? Can (base oil plus diesel/kerosen) = home heating oil?

2229

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why cone formation during dissolution?

845

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in gas chromatography what is the difference between gas flow rate and average linear velocity ?

2652

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Difference between hlaf and rlaf

2167

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What is third generation HPLC Columns?

2033

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