Answer Posted / amol

because , when manufacturing of column is done different
parameter is affected which is given below , due to this
each column is unique tho it is same type.

column parameter

column pressure
parical size
carbon density
dead voulume of the column
end fitting
end capping of the column.
silica used.

Hplc System Parameter

length of tubing.
internal dia. of tube.
void volume of system.
pump working.
flow rate.
end fittings.
ETC....

how you start RS method development when for new product?

715

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What is dose dumping? why require to do?

945

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can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?

2177

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how can give the expiry period and restadardisation of volumetric solution

2582

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Why perchloric acid used for potentiometric titration

2674

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what is partion and column chromatography

2382

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How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2383

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1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1842

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Explain the relations between number of carbon atoms in alkanes and retention time ?

2138

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how you determine moist.of NaOH sol or NaOH flacks

2214

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What is the principle of Thermal conductivity detector and FID?

2724

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pharma industries oriented

2231

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process of Diclofenac sodium,IP.

2201

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what is mean by 40 in the dissolution basket mesh size?

783

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what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

886

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