Answer Posted / abdulkalim

Parameters involved during initial stage of Analytical
Method development:

1. Optimization of Mobile Phase
2. Selection of Buffers
3. Selection of Ion pair reagent
4. pH of buffer/mobile phase
5. Composition of Mobile Phase
6. Selection of Column
7. Optimization of Analyte signal
8. Objectives of Seperation
8.1 Analysis time
8.2 Resolution
8.3 k factor (Capacity factor)
8.4 Peak height
8.5 Asyymetry
8.6 Theoritical Plates
9. Flow rate

why multimedia dissolution require to do?

812

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why require to add enzymes in capsules dissolution only? is it require to tablet also?

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Tell me about analytical method validation in QC

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Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

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could negative ions be produced by bombardment process in mass spectrometry?

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what is the acceptance criteria for enteric coated tablets in 0.1n hcl validation in each parameter?

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