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how we are selecting the dissolution medium volume like
250ml, 500ml, 900ml, 1000ml?

Answers were Sorted based on User's Feedback



how we are selecting the dissolution medium volume like 250ml, 500ml, 900ml, 1000ml?..

Answer / manish kumar rai

The volume of disso media is basically the sink condition of the drug substance for which dissolution is to be done. Generally 3 to 5 times volume that require in order to form a saturated solution of said drug. Let a drug substance forms a saturated solution using 300 ml then for dissolution of such drug formulation required at least 900 ml or more disso media.

Is This Answer Correct ?    9 Yes 2 No

how we are selecting the dissolution medium volume like 250ml, 500ml, 900ml, 1000ml?..

Answer / raghavendra

In stomouch fluid content is 250ml, in interstine it is
500ml, in git fluid content 900ml

Is This Answer Correct ?    0 Yes 12 No

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