Exactly how fast is PatternHunter when comparing two DNA
sequences?
Answer / guest
PatternHunter was used to compare the Human Genome (3
Gbase) against 16 million reads of the Mouse Genome (3
coverage, 9 Gbase total). It took only 21 days using a
Pentium 3/700 MHz desktop computer with 1G of RAM. On the
same machine and at the same sensitivity, Blast would take
years.
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Suppose you used the NCBI Blast server to look for a match to a fruit-fly gene. Suppose further that the best alignment contained this section of an alignment: Hit from database: XXXXXXXXXXXXXXNFSTSQ user sequence: SLEAEAAPASISPSNFSSSQ What do the Xs signify?
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NLO : RPS : : ? : ZXA
Exactly how fast is PatternHunter when comparing two DNA sequences?
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