Answer Posted / pradeep

Least count is lowest value measure by any measuring instrument accurately. If a measuring ruler have divisions in Centimeter and milimeter then least count is 0.1 Centimeter or 1 mm. In case of instrument like balance least count given by instrument manufacturer because capacity of balance to measure lowest value is checked during it's manufacturing. If it's not given then it will be measure not get calculated. The lowest weight measured with accuracy of +/- 0.001% is consider as it's least count.

if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?

970

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UV and PDA detector, which have less signal to noise ratio?

1124

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what you do when compound having dwel wavelength?

738

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Which type of column should i use to check the purity of high molecular weight protein using HPLC reverse phase column chromatography? Hi everyone. I wanna to check the purity of high molecular weight protein (collagen) with MW of ~130 kDa using a HPLC. I know C18

1908

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How require to develop GC method? how to select diluent, GAS, column selection and other chromatographic conditions?

720

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why require to do water content for drug product?

819

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how to decide for one product require water content or LOD?

774

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What are modes of quantification in related substances

2158

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As per ICH related substances stability trend limit from initial to shelf life

3242

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why are measure gas flow " ml " in Gas chromatography

1649

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why we should take dst factor for below 1%moisture samples

2658

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Why six unit used for precision?

1337

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How can I develope method of dissolution by HPLC OR UV

2401

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How can we calculate offset value pH measurment

1497

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what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

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