Why sulpuric acid only used to ROI but not used nitric acid
and some other acids?
Answer Posted / satish kumar
Basically H2SO4 is strong acid than other acids so it can react with any inorganic impurities into organic compound then it converts into their sulphates salt ..... sulphates are more stable at high temperature while compare with any other acids like nitric acid also....
Sulphates are easily reacts with inorganic compounds to be form as salts due to its strong oxidising nature and more stable but incase of nitrates its occurs in slowly and not stable at high temperature up to 600...
| Is This Answer Correct ? | 7 Yes | 0 No |
Post New Answer View All Answers
acceptance criteria for lod & loq by standard deviation of response and slope??
What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?
If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?
how you start the solubility study?
identification is for unknown? qualification for known? reporting for LOQ?
in DMF having extra impurities and in api COA also having extra imp than USP or BP product then how require to proceed?
what is the extinction coefficient for Indomethacin or at 319nm wave length.
what type of question will ask in the interview of lab chemist.
could negative ions be produced by bombardment process in mass spectrometry?
all types of questions asked at the cipla interview
In HPLC calibration, caffeine is used as primary standard for wave length calibration due to caffeine is having dual maxima at 273 & 205 nm and one minima at 245 nm. Any body can give reference of these details from any pharmacopeia (with chapter no.) or any other authentic guideline?
What is aggregate and fragments in SEC?
How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?
What is the difference between purge septum flow and column flow in gas chromatography?
if you have given one product then how you determine the impurity in that?