What does theoretical plates number mean?
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In IR spectra, generally a molecule vibrates without apply emr or ir light?
what is mean by covalidation
2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.
For titration in anhydrous media with perchloric acide, if lack of titrator, Which indicator is been used for replacement. How calculate pH of test solution to choose suitable indicator?
What is similarity factor?
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
In which situation we require to prepare the standard solution from sample in Related substance method?
What is the formula for relative diffrence for standard solution in solution stability in validation?
Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc
in which situation require to take incident in validation?
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
what is turbidimetric titration?Give 2 examples.
What is the principle of Thermal conductivity detector and FID?
Identify problem faced when mass spectroscopy is used with HPLC system ?
WHAT IS THE USE OF STARTER ?????????
