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what is the need of calulation of RRF of impurity in HPLC
analysis?

Answer Posted / laura

Hi,
When a different marker is used to find out which impurity is seen in the chromatogram due to not being availble, and a really similar compound is used (in this case the salt ) how can I calculate the RRF of the compound which was not available in regard to the one that was tested? I calculated the RRF of the compound tested, but how can I extrapolate to the one I am looking for?

Many thanks in advance,

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