Interested to Buy Any Domain ? << Click Here >> for more details...
Answer Posted / vinod kumar uppalli
The SI-OH functional groups tend to ionize at at higher pH into negatively charged group. This will lead to secondary interaction between Si-O negative and basic analytes. This leads to tailing of peak, to overcome from this issue columns are end capped.
| Is This Answer Correct ? | 0 Yes | 0 No |
Post New Answer View All Answers
if your product is soluble in 0.1n hcl and water then which you choose as media from these 2 media?
can we use the same detector in HPLC as well GC and what could be the differences we can find in the final chromato graph in any aspects?
In IR spectra, generally a molecule vibrates without apply emr or ir light?
What is the formula for relative diffrence for standard solution in solution stability in validation?
why require the ph, buffer during hplc mobile phase?
Related substance method equivalency on control sample or spiked sample?
In the HPLC Calibration done wavelength accuracy done between 200nm-280nm .but not done remaining 300-400nm not done ?
how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.
why we are using hexane in calibration of number of drop per mL
what is %labelled amount in content uniformity of dosage unit and its calculation?
In which situation we require to prepare the standard solution from sample in Related substance method?
What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)
acceptance criteria for lod & loq by standard deviation of response and slope??
Is it nessesary all multimedia dissolution require descriminatory?
Which parameters require to do in tech transfer?
