Answer Posted / srikanth

Potency Means excluding of all possible impuities-Organic and inorganic(water(LOD,MC), residual solvents, unknown, known impuities, ROI....so on)
Potency=100-all posiible impuities
Assay means it will be calculated with respect to standard.

What is the formula for relative diffrence for standard solution in solution stability in validation?

740

---

mode of absorption in alimentary canal?

2341

---

how require to select dissolution media? what is discrimination?

746

---

I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

3489

---

if you get peak in blank then what require to do?

911

---

How we can identify process related and degradation impurity in single method with short period?

760

---

How to set analytical specification for combination products?

774

---

What is dose dumping? why require to do?

874

---

What is stray light in uv what are units for stray light

1565

---

What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7477

---

In Dissolution Test why limit is define Q+5% what is the role of +5%.

3045

---

1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1792

---

in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

718

---

acceptance criteria for lod & loq by standard deviation of response and slope??

2534

---

How we choose the mobile phase for method development.?

1164

---