Answer Posted / aamir sohail

it converts most of the metals into their sulphates but not all like phosphorus does not converted into sulphates it remain same till the end of the test, than these metal sulphates further proceed for heavy metal test that how much amount of which metal present in it...

in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

813

---

why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?

1665

---

how require to select dissolution media? what is discrimination?

765

---

What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

785

---

1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1814

---

2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

2182

---

How to establish relative response factor for hplc. Why it is required?

1178

---

analytical method validation require to with respect to release specification or shelf life specification?

755

---

While performing TOC sst analysis Zero shift disabled & sample analysis zero shift enabled why?

2810

---

What is control room temperature and which guide line says?

1604

---

for inorganic molecules require to do RS, Assay and disso?

703

---

in dissolution if one bowl got 70 percent 2nd bowl got 80 percent and 3rd bowl got 90 percent then how proceed?

731

---

Which is the highly polar and highly non polar column in HPLC?

2263

---

how you start RS method development when for new product?

687

---

in sampling of raw material which side is pasted sampled labels

1807

---