How to fix the concentration for RS by HPLC
- 10 Answers
- 44061 Views
- Intas, Reddy Labs, I also Faced
- E-Mail Answers
Answer Posted / ram
The common procedure for fixing the LOQ is assuming u r specification as 100 % and we have to achieve LOQ below 50% of specification, here impurities are may be known or unknown.
for exm. known imp limit is 1.0 % then u should try to get LOQ below 0.5%, however if u try for very low level then it is well n good.
All unknown impurities will have spe of 0.1% limit and we have to do validation of unknown with active .
| Is This Answer Correct ? | 4 Yes | 1 No |
Post New Answer View All Answers
we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion
What is intact assay method development.....?
AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?
in each media we require to use SLS? how to proceed?
if instrument calibration fails then what require to do?
from where i get mortar pastle for glass bottle crush? it's required for testing of it?
We use Potassium Dichromate solution for the calibration of UV-Visible Spectrophotometer in UV region. My question is to calibrate visible region which solution could be used in photometric accuracy
How to calculate coreletion coefficient
why holium oxide prepared in 10% HCLO4 SOLUTION
How can the GC or HPLC method is selected to determine the impurity profile in drug product?
cefoperozone and sulbactam inj. hplc test method
How to determine the EDTA content by potentiometry titration in Ceftriaxine sodium
how to select short coloum and long coloumn for new molecule
on the basis of bcs class how to proceed the solubility?
Why six unit used for precision?
