why inject diluted standard solution in related substance
analysis by HPLC?
Answer Posted / yantesh varshney
If Impurity peak have very low response in this case we prepare diluted standard as per criteria generally at 1 % level to check and compare the impurity with in limit .
Is This Answer Correct ? | 6 Yes | 0 No |
Post New Answer View All Answers
Ratio of Water and Acetonitrile(diluent) is not recommended to use in cleaning method validation,why?
if peak get problamatic then what require to do?
If change in specification which parameter require to do for validation? if change in chromtographic condition then which parameter? if api change then which parameter? if change composition then which parameter? if old method not work out then whicj parameter? if additional one impurity added then which parameter of validation require to do on above each conditions? elaborate separately
How much is the standard area for glc analysis
Why irmoisture balance is used for corrugated box moisture testing
Why a1% value is used for some product ? What is the criteria for selection a1% value ?
what is the difference between potentiometric titration and karl fischer titration?
what is the purge flow & how to calculate
In which situation we require to prepare the standard solution from sample in Related substance method?
why sre you used Potassium hydrogen phthalate in standarisation of 1N NaOH and 0.1 N Perchloric Acid?
if you have given a blank water how you analyse by general analytical techniques?
What is split ratio in Gc? Splitless? how requirr to select?
why should we perform dissolution PVT calibration only by UV spectrometer, not by HPLC ?
From where require to take the RLD sample?
for which product require to do content uniformity? what is limit of cu?