Difference Between Purity And Potency?
- 3 Answers
- 12317 Views
- Dr Reddys, Reddy Labs, Watson Pharmaceuticals, I also Faced
- E-Mail Answers
Answer Posted / naveen gutta
Purity:
It is calculated by area normalisation method, it can be directly find out by chromatograms obtained from HPLC.
% Purity = (Area of desired peak / Sum of area of all peaks) x 100
Assay:
It is calculated against standard. It may be of following types:
1) On as is basis = (Area of sample / Area of standard) x (conc. of standard / conc. of sample) x potency or assay of standard
2) On anhydrous basis = (Assay on as is basis / 100 – moisture) x 100
3) On dried basis = (Assay on as is basis / 100 – LOD) x 100
Potency:
100 – (moisture or LOD + residual solvents + heavy metals + sulphated ash + impurities)
| Is This Answer Correct ? | 2 Yes | 0 No |
Post New Answer View All Answers
what we do when calibration of any instrument is fail ?
When we change water of Hygrometer?
What skills would you look for while hiring a pharmaceutical representative?
if one drug is acidic in nature and the other drug is basic in nature, e.g. desloratadine is soluble in acidic environment i.e 0.1N HCL whereas Montelukast Sodium is soluble in basic environment i.e. .2% SLS. How can we choose a common media for there Dissolution?
What is your work experience in pharmaceutical field?
why we use SLS in dissolution
which is the best pharma company u think
hello,am milan mohite,i have completed B.PHARM,in 2008.and now do M.B.A from ignou,and D.P.P.M,from IPER{PUNE},please suggest me best coaching institute in pune for drug inspector,and send me model question paper for prepration of D.I. on my e.mail id - milan_mohite@yahoo.in Thanks.
plzzz mail me question papers and syllabus of mpsc's and upsc's drug inspector's exam.and details whn da exm is going to be.. my e-mail id is shubhg_2007@yahoo.com.thanx..
What do you mean by Q+5 in dissolution?
why we use matrixing method in stability study and on what basis time points are selected?
How to select HPLC column for a particular product?
You have been allotted a territory and given a list of physicians. How would you start calling?
besides Signal & noise ratio how calculating LOD & LOQ?
What is the difference of vacuum pressure and vapor pressure?
