Why are use KF reagent to measure water content & why not any other reagent?
Answer Posted / naveen gutta
Advantage of analysis[edit]
The popularity of the Karl Fischer titration is due in large part to several practical advantages that it holds over other methods of moisture determination, including:
High accuracy and precision - typically within 1% of available water, e.g. 3.00% appears as 2.97 - 3.03%.
Selectivity for water
Small sample quantities required
Easy sample preparation
Short analysis duration
Nearly unlimited measuring range (1ppm to 100%)
Suitability for analyzing:
Solids
Liquids
Gases
Independence of presence of other volatiles
Suitability for automation
Linearity - single-point calibration, no calibration curves necessary
In contrast, loss on drying will detect the loss of any volatile substance.
The major disadvantage is that the water has to be accessible and easily brought into methanol solution. Many common substances, especially foods such as chocolate, release water slowly and with difficulty, and require additional efforts to reliably bring the total water content into contact with the Karl Fischer reagents.
| Is This Answer Correct ? | 1 Yes | 0 No |
Post New Answer View All Answers
Explain penicillin, antiseptic, artificial insemination, hydrophobia, cataract, memingitis, mumps?
What is gas sterilization?
what are Threats
why single injection in related substance & dissolution but why not in assay ?
What do you mean by a confirmatory test?
Explain mumps?
What is the principal of particle size analyzer?brief explain instrumentation?
why we have to use particular buffer only for dissolution.
what is your perception of a typical day for a pharmaseutical representative?
explain the selection criteria of a control
What is blank?
Why mineral oil or light liquid paraffin is used for ir analysis
What are infectious diseases?
Why pipetting training is crucial for clinical technician?
Explain cataract?