Why are use KF reagent to measure water content & why not any other reagent?

Answer Posted / naveen gutta

Advantage of analysis[edit]
The popularity of the Karl Fischer titration is due in large part to several practical advantages that it holds over other methods of moisture determination, including:

High accuracy and precision - typically within 1% of available water, e.g. 3.00% appears as 2.97 - 3.03%.
Selectivity for water
Small sample quantities required
Easy sample preparation
Short analysis duration
Nearly unlimited measuring range (1ppm to 100%)
Suitability for analyzing:
Solids
Liquids
Gases
Independence of presence of other volatiles
Suitability for automation
Linearity - single-point calibration, no calibration curves necessary
In contrast, loss on drying will detect the loss of any volatile substance.

The major disadvantage is that the water has to be accessible and easily brought into methanol solution. Many common substances, especially foods such as chocolate, release water slowly and with difficulty, and require additional efforts to reliably bring the total water content into contact with the Karl Fischer reagents.

Is This Answer Correct ?    1 Yes 0 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

Explain mumps?

602


Explain penicillin?

601


can any one give me the question bank for Lab Technician am going to appear for my HAAD exam on the 29/4/10. Please send me the Qs. my mail Id is petula_dsouzaa@yahoo.com Please help. thks.

2188


How do you think you would get a physician to switch to drug?

3100


Why pipetting training is crucial for clinical technician?

926






Why 6 tablets are used in dissolution and DT test ?Is there any specific reason behind it ?

4096


Explain artificial insemination?

589


what is your perception of a typical day for a pharmaseutical representative?

2031


What is laboratory centrifuges?

692


What is gas sterilization?

802


What is dynamic range?

686


What clinical lab audit is and what are the areas you can do clinical audit?

702


IN OOS SAMPLING ERROR HOW CAN WE ADDRESS , OR HOW CAN WE EXPLAIN AUDITOR ABOUT SAMPLING ERROR

2105


What is Calibration Curve?

670


if drug batch rejected in pharma industry thn what techniques are made to clear the batch?

2206