What is the principle of GC/HPLC ?

Answer Posted / srikanth narla

GC works on the principle of PARTITION CHROMATOGRAPHY. In this Stationary phase is a liquid and mobile phase is a Gas.

HPLC works on the principle of ADSORPTION CHROMATOGRAPHY. In this stationary phase is a solid and mobile phase is a liquid.

Is This Answer Correct ?    51 Yes 1 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

what is procedure of actual procedure for registration of drug?

1462


WHY pKa value is more important than pH value of the mobile phase in HPLC?

1263


What is the formula to determine the concentration of M of a solution given the % transmittance? Use %T = 43.7 as an example.

2122


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

6924


how you start RS method development when for new product?

294






Colorimtry

1179


how can give the expiry period and restadardisation of volumetric solution

2059


when we talk about change in entropy we consider total entropy means of surround +entropy of system but when we talk about change in Gibss free energy we consider entropy of system.explain with reason.

1526


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

6872


How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?

1311


why require to add enzymes in capsules dissolution only? is it require to tablet also?

273


Why a1% value is used for some product ? What is the criteria for selection a1% value ?

1876


From where require to take the RLD sample?

286


What is shaking level in GC?

334


if you given one product then which tests you will perform?

323