What is the difference between Chromatograhic Purity And
Related substances
Answer Posted / sameer jagtap
chromatographic purity is calculated by area normalisation
method it gives the percentage of the main product and
related substances by HPLC gives you the Impurity profile
(known + unknown impurity)present in the product.
Is This Answer Correct ? | 3 Yes | 5 No |
Post New Answer View All Answers
How can the GC or HPLC method is selected to determine the impurity profile in drug product?
Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6
mode of absorption in alimentary canal?
if your impurity coeluting with each other in that situation how require to set specification? is it acceptable?
Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?
If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?
What is dose dumping? why require to do?
Related substance method equivalency on control sample or spiked sample?
how decide the clining method and cleaning method validation require for this perticular products?
Ph meter can show more than 14 ph reading? Why ph range in between 1 to 14 only?
IS THERE ANY EQUIPMENT TO CHECK AND CALCULATE THE POLARITY OF A LIQUID?
How we can identify process related and degradation impurity in single method with short period?
in OSD forms require to use gas chromatography?
Which products will produce when acetic anhydride reacts with Ter-butanol, Sec-butanol, Iso butanol, Dimethylamine etc.
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?