Golgappa.net | Golgappa.org | BagIndia.net | BodyIndia.Com | CabIndia.net | CarsBikes.net | CarsBikes.org | CashIndia.net | ConsumerIndia.net | CookingIndia.net | DataIndia.net | DealIndia.net | EmailIndia.net | FirstTablet.com | FirstTourist.com | ForsaleIndia.net | IndiaBody.Com | IndiaCab.net | IndiaCash.net | IndiaModel.net | KidForum.net | OfficeIndia.net | PaysIndia.com | RestaurantIndia.net | RestaurantsIndia.net | SaleForum.net | SellForum.net | SoldIndia.com | StarIndia.net | TomatoCab.com | TomatoCabs.com | TownIndia.com
Interested to Buy Any Domain ? << Click Here >> for more details...

water is more polar than acetonitrile.but in reverse phase chromatography peaks elute earlier when we increse Acetonitrile.what is the reason.

Answer Posted / ronda.venki

based on polarity of stationary phase and sample, normally
reverse phase columns having stationary phase non polar so
ACN INCREASE means elution strength increased bcz of
interactions of stationary phase and product

Is This Answer Correct ?    16 Yes 2 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

What is the diffrence in japan mkt requirement in analytical method validation over US?

772


2. Two grams of Benzoic acid are dissolved in 200 ml of water and extracted with 200 ml of diethyl ether. The distribution coefficient of benzoic acid is 100, and its dissociation constant is 6.5 10-5. Calculate the distribution ratio (D) of benzoic acid at pH 2, 5, and 6. 3. Calculate D at pH 2 to 10 (1 unit apart) in the above problem, and plot D versus pH.

2263


If suppose 10 methods of dissolution given in pharmacopoeial for single content product then which method out of 10? or all 10 require to follow?

1041


If vendor having more imp than monograph then how to proceed? and how to set spec?

1004


why cone formation during dissolution?

847


Why potassium dichromate is used in calibration of uv?

2038


What is aggregate and fragments in SEC?

2157


what is mean by nitrosamine impurities?

1117


How can the GC or HPLC method is selected to determine the impurity profile in drug product?

7676


iam usig ph buffers merk. manually how to prepare ?

2328


How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3404


How do we quantify crystaline and amarpous forms by using (NMR, XRD)spectroscopic techniques? Which any others instruments are useful for this quantification? explain

2438


why we are using hexane in calibration of number of drop per mL

1793


why does used dry caffien in HPLC calibration?

2079


in api coa contains only process impurities and in product coa contains degradation impurities?

734