Answer Posted / nikhil gandhi

Based on ICH Guideline there are many method given to
identify LOD and LOQ, but most useful method is slope and
residual standard deviation is used.

LOD : 3.3 X sigma/ Slope
LOQ : 10 X sigma/ Slope

Sigma : Residual Standard Deviation

what is turbidimetric titration?Give 2 examples.

2670

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what is difference between UV - VISIBLE MODEL NO like 1600,1601,1700 etc ? plz explain me

2684

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How do we get end points and how many end points are possible for citric acid and di-acid not theorotically answer should be given practically.

2584

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what is partion and column chromatography

2392

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Please tell me about the pH of Polycaboxylic ether is it in the 5-6 range ever or more than 6

2609

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how many types of balance calibration test?

2300

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function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

2669

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why require to do water content for drug product?

829

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what is the importance of peak purity in HPLC and how we can calculate through manul(not software)?

4488

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I have compare C2H2-air and C2H2-N2O flame AAS on determination calcium. Both use same range of std to plot calibration curve. (2-6ppm) When i measure the sample with phosphate, KCl and LaCl, C2H2-N2O flame give false positive result, around 0.5ppm. When i measure the sample with phosphste, KCl and EDTA. C2H2-N2O flame also give 0.5ppm false positive. But both above mentioned sample would not give false positive when measured by C2H2-air flame. What is the reason?

3540

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WHY pKa value is more important than pH value of the mobile phase in HPLC?

1769

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how can give the expiry period and restadardisation of volumetric solution

2596

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CAN WE DETERMINE THE PEAK PURITY IN GAS CHROMATOGRAPHY ANALYSIS?

1210

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using gradient pressure in gas chromatography are not ?using gradient pressure why

3390

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UV and PDA detector, which have less signal to noise ratio?

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