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What is the difference between Capillary column and Packed
column.
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Answer Posted / balla reddy. p
Packed columns are more durable, has higher sample capacity
(Sample load) ,more phase selectivity, and has lower cost.
The disadvantages are larger amounts of bleed, smaller
number of theoretical plates/efficiency (i.e. separating
power for similar compounds is much low) and particle loss
into the detector. So it can not be coupled with MS or other
sensitive detectors.
Capillary columns have the advantage of larger theoretical
plate numbers /efficiency /higher resolution and inertness.
They excel at low ppm to ppt level analysis. They are
limited in phase selectivity options but their low carrier
gas use to the detector and low bleed characteristics allows
Mass Spectroscopy and other sensitive detectors to be used
effectively.
The use of bonded phases permits higher oven temperatures to
be used in applications.So capillary column withstand higher
column oven temperature compared of packed column.
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