what is ramachandran plot?what r its applications?
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Answer Posted / baljinder gill
Atoms were treated as hard spheres and dihedral (φ and ψ) angles which cause spheres to collide correspond to sterically disallowed conformations (atoms come closer than sum of van der Waals radii) sterically allowed conformations of the polypeptide backbone (energetic stabilized).
Used computer models of small polypeptides to systematically vary φ and ψ with the objective of finding stable conformations. Ramachandran plot tells about the permitted (allowed)and disallowed rotation of dihedral angles and gives information about the stabilized structure or allowed structure of proteins (why alpha helix is more stable than beta sheet).
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