Answer Posted / satheesh kumar

semicarbazide is derivative of urea,two compunds separate
through Non-Aqueous reverse phase chromatography.
select columns also like a polar column namely silica column
(YMC PAck Silica,Hypersil silica)

what is impurity profile. how to interpret this impurity profile to a drug product or drug substance.

2209

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if you get peak in blank then what require to do?

490

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How would you decide dissolution medium for NCE compound of class I drug

1711

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How we performed the force degradation for drug substance, is any specific guideline is available for each parameter(Acidic, basic, oxidation,heat)? what conditions you mentained for above parameters.

1801

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How can we calculate "confidence interval" in analytical method validation? Pl. explain with example.

3602

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Qc interview questions

1253

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why require to add enzymes in capsules dissolution only? is it require to tablet also?

272

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what is the difference between potentiometric titration and karl fischer titration?

2429

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why multimedia dissolution require to do?

312

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how you confirm the assay method?

293

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for inorganic molecules require to do RS, Assay and disso?

256

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What is similarity factor?

731

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Hi sir if any product monograph not given known impurities (may be 5 impurities) specifications then how we require to proceed for inhouse formulation?

285

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In HPLC Calibration, On which basis RSD Limit of noise test is fixed (NMT 33.0 % )

2962

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What is stray light in uv what are units for stray light

1026

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