How to calculate LOD & LOQ in HPLC Validation Method
Answer Posted / rakesh p. kotkar
Based on standard deviation of the response and the slope
obtained will be calculated as:
Limit of Detection (LOD):
DL= 3.3(ASD/Slope)
Limit of quantification(LOQ):
DL=10(ASD/Slope)
| Is This Answer Correct ? | 10 Yes | 3 No |
Post New Answer View All Answers
analytical method validation require to with respect to release specification or shelf life specification?
why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space
in stress study if your api not soluble in hcl naoh h2o2 then what require to do?
What is similarity factor and its use in api strength?
What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)
Why Ethanol is Used for Standardization of GC Head space?
mahagenco syllabus for the post of chemist
what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?
What are modes of quantification in related substances
how many types of balance calibration test?
what is mean by nitrosamine impurities?
Identify problem faced when mass spectroscopy is used with HPLC system ?
if rsd failed then what require to do?
in sampling of raw material which side is pasted sampled labels
What is delay volume?