Golgappa.net | Golgappa.org | BagIndia.net | BodyIndia.Com | CabIndia.net | CarsBikes.net | CarsBikes.org | CashIndia.net | ConsumerIndia.net | CookingIndia.net | DataIndia.net | DealIndia.net | EmailIndia.net | FirstTablet.com | FirstTourist.com | ForsaleIndia.net | IndiaBody.Com | IndiaCab.net | IndiaCash.net | IndiaModel.net | KidForum.net | OfficeIndia.net | PaysIndia.com | RestaurantIndia.net | RestaurantsIndia.net | SaleForum.net | SellForum.net | SoldIndia.com | StarIndia.net | TomatoCab.com | TomatoCabs.com | TownIndia.com
Interested to Buy Any Domain ? << Click Here >> for more details...

How to calculate LOD & LOQ in HPLC Validation Method

Answer Posted / rakesh p. kotkar

Based on standard deviation of the response and the slope
obtained will be calculated as:

Limit of Detection (LOD):
DL= 3.3(ASD/Slope)


Limit of quantification(LOQ):
DL=10(ASD/Slope)

Is This Answer Correct ?    10 Yes 3 No



Post New Answer       View All Answers


Please Help Members By Posting Answers For Below Questions

analytical method validation require to with respect to release specification or shelf life specification?

750


why we use Dichlorobenzene.nitrobezine.t-butyldi sulhate.for calibration of gc Head space

2221


in stress study if your api not soluble in hcl naoh h2o2 then what require to do?

806


What is similarity factor and its use in api strength?

1262


What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7487


Why Ethanol is Used for Standardization of GC Head space?

4174


mahagenco syllabus for the post of chemist

6439


what parameters we will consider while developing a HPLC method and how we confirm our HPLC method is valid?

3647


What are modes of quantification in related substances

2123


how many types of balance calibration test?

2263


what is mean by nitrosamine impurities?

1025


Identify problem faced when mass spectroscopy is used with HPLC system ?

1818


if rsd failed then what require to do?

780


in sampling of raw material which side is pasted sampled labels

1800


What is delay volume?

1337