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A principal difference between prokaryotic and eukaryotic
DNA replication is

a) completely different proteins/enzymes in eukaryotes

b) multiple origins in eukaryotes

c) no requirement for topoisomerase activity in prokaryotes

d) the absence of a nucleus in prokaryotes

Answer Posted / zainab

Actually,
1. Enzymes for DNA replication only found in eukaryotes are certain types of DNA ploymerases and telomerase.
Enzymes only found in prokaryotes are the different DNA ploymerases and DNA gyrate.
Enzymes common to both are helicase, primase, topoismerase and DNA ligase.
Answer: Yes
2. Yes in eukaryotesn(linear double stranded DNA) there are multiple origins of replication at which replication forks are formed in replicons. Prokaryotes only have a single origin of replication and thus a single replication fork formed.
Answer: yes
3. False. In bacteria, in addition to topoismerase, DNA gyrase also induces negative supercoiling.
4. No nucleus in prokaryotes and hence transcription is coupled to translation (while RNA transcript is being synthesised, a 70s ribosome will attach to the 5' end). True.

Hope is helped. How long ago was this posted?

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