What is the reason for using the 900ml of dissolution medium
- 16 Answers
- 74241 Views
- Cipla, I also Faced
- E-Mail Answers
Answer Posted / amit
Selection of disoslution media depends on the sink
condition which means, three time the highest dose of drug
dissolving in 250 ml of media. So, if your drug diosslves
in 250ml you can select 250ml as mediavolume or depending
on the solubiliy you can go upto 2 lts with proper
justification.
Remember the selection of dissolution media volume is only
to get whole amount of drug dissolved and sholud be able to
quantifiy it.
| Is This Answer Correct ? | 33 Yes | 6 No |
Post New Answer View All Answers
What is gelatinization?
AT WHAT CONDITIONS WILL YOU ANALYSE A SAMPLE,WHICH ARE PRESERVED AT OTHER THAN THE AMBIENT CONDITIONS?(ie COLD STORAGE SAMPLES BELOW 20* CENTIGRADE?
how will you do the prep for unstable componds?
In Dissolution Test why limit is define Q+5% what is the role of +5%.
What is the calibration of uv process and preparation
My question about gas chromatography sulfur chemiluminsecence detector. I test unknown sample gas by GC-SCD (calibrated ) and the result of *H2S is 279 PPM , *but when I test the same sample with the GC-TCD (calibrated ) the value of *H2S is 2500 PPM . I'd like to inform you that both GCs are calibrated and have very good operation conditions with stable parameters . the question is if the sample gas with higher H2S over detection limits of SCD detector (1000 ppm). why the result it 279 ppm Best regards
For standardization of volumetric solutions, acceptance limit for concentration is considered as 10% of nominal concentration and %RSD as NMT 0.2% (for appropriate no. of replicates). But , if %RSD has not met, what should be further action?
how you fix the limits of impurities?
In the isomers,enantiomers give the only physical properties present such that no chemical properties present.
We use hicrome 10 cxs column in hplc analysis....pls tell me.. what is the meaning of 10 cxs?
what is the disso medium for tropsiun chloride
Why sometime potassium ortho phosphate mix with acetone use for sample preparation for hplc
for inorganic molecules require to do RS, Assay and disso?
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
