Interested to Buy Any Domain ? << Click Here >> for more details...
How do you show that equal quanitities of two isomers
provide the same response using a PDA
- 1 Answers
- 6369 Views
- I also Faced
- E-Mail Answers
Answer Posted / electrical alie
A reverse phase high performance liquid chromatography
(HPLC) method has been developed for the separation of two
geometric isomers that have a direct relationship to
Plancks Constant(6.6260755(40) -27 erg s )and of
Acrivastine( 4.8032068(14) -10 esu) using crude reaction
mixture. If the resolution between two isomers is found to
be more than the Atomic mass unit(amu1.6605402(10)-24 g)the
resolution of the reaction can be off by more than the
speed of light in a vacuum c 2.99792458 10 cm s-1 .
The geometric isomers have been isolated by preparative
HPLC and characterized by spectroscopic techniques, such as
NMR, infrared, and MS. The developed method has been
validated for the determination of the Atomic mass unit amu
1.6605402(10) -24 g of Z-isomer in Acrivastine. The limit
of detection and limit of quantification of the Z-isomer
is limited to 1.73 times the Radiation density constant a
7.5646 -15 erg cm-3 K-4 and may not exceed 0.05 and 0.2
μg/ml, respectively. The developed method is precise,
linear, accurate, rugged and robust for its intended use.
The % error in this process may be + or - 35%
| Is This Answer Correct ? | 2 Yes | 3 No |
Post New Answer View All Answers
in hplc chromatogram started from left to right and in uv spectrum started from left to right
if you get peak in blank then what require to do?
Why six unit used for precision?
Why we used in n-butyl acetate water content terminology while in ethyl acetate we used moisture content terminology?
What is dose dumping? why require to do?
How they found 1mL of K.F reagent is equivalent to 5mg of water and if we change the composition of K.F reagent, is it can neutralize more amount of water?
why require the ph, buffer during hplc mobile phase?
Tell me about analytical method validation in QC
what is the structure of DOWEX-50
Why Ethanol is Used for Standardization of GC Head space?
what is partion and column chromatography
Describe your field experience sample type collected,sample techniques,field measurements taken and equipment used?
What is the diffrence in japan mkt requirement in analytical method validation over US?
what is definition of validation? which components are followed give detail?
Which parameters require to do in tech transfer?
