water is more polar than acetonitrile.but in reverse phase chromatography peaks elute earlier when we increse Acetonitrile.what is the reason.
- 10 Answers
- 49013 Views
- Matrix, I also Faced
- E-Mail Answers
Answer Posted / prasad
based on the solubility of the drug.Most of the drugs are insoluble in water
| Is This Answer Correct ? | 9 Yes | 10 No |
Post New Answer View All Answers
if tech transfer fails whay require to do?
How would you decide dissolution medium for NCE compound of class I drug
What is the principle of Thermal conductivity detector and FID?
In BP2013, Loperamid HCl monograph. Assay by titration with 0.1N sodium hydroxide using hydrocloric acid 0.01N and reading the volume added between the 2 points of inflexion. I have a question that if the diluent solvent is ethanol is certainly consumed a amount of volume of titrant, so this volume must be eliminated on the result calculation or not apart from first point which is subtracted above.
Why to use propyl paraben in HPLC gradient calibration
how decide the clining method and cleaning method validation require for this perticular products?
some product having water content method with pyridine and ethylene glycol mixture instead of methanol? how they are selecting and methanol is not suitable solvent how ?
why require to add enzymes in capsules dissolution only? is it require to tablet also?
what are risk assement in the analytical qbd?
A ha tc is actual defination of retention time?
Which parameters require to do in tech transfer?
why we are using hexane in calibration of number of drop per mL
What is the requirement for brazil in the analytical method vslidation comparr to ich?
Difference between hlaf and rlaf
could negative ions be produced by bombardment process in mass spectrometry?
