Answer Posted / venkatesh

For pharmacopeial purposes, residual solvents in
pharmaceuticals are defined as organic volatile chemicals
that are used or produced in the manufacture of drug
substances or excipients, or in the preparation of drug
products. The residual solvents are not completely removed
by practical manufacturing techniques. Appropriate
selection of the solvent for the synthesis of a drug
substance or an excipient may enhance the yield, or
determine characteristics such as crystal form, purity, and
solubility. Therefore, the solvent may sometimes be a
critical element in the synthetic process. This General
Chapter does not address solvents deliberately used as
excipients nor does it address solvates. However, the
content of solvents in such products should be evaluated
and justified.

how a particular wavelength can be different for a particular compund while analysing by uv and by HPLC.

2246

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What is the Formula for coreletion coefficient in plhplc calibration

1773

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if you given one product then which tests you will perform?

664

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What is the difference between Discriminating media and DPDM(Dissolution Profile with Different Media)

7473

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which situation gc hs and gc als require to use?

721

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if peak get problamatic then what require to do?

741

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What is the accrptance criteria in RSD for RS method precision on basis of impurity percentages?

766

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Difference between the quantitative analysis and qualitative analysis?

1105

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why cone formation during dissolution?

729

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function of detecter in hplc ,gc and spectroscopy? function of carrier gas in gc?

2609

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what type of question will ask in the interview of lab chemist.

3261

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What is the use of tlc and hplc? And when and where use?

1100

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Why potassium dichromate is used in calibration of uv?

1922

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in each media we require to use SLS? how to proceed?

721

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Why perchloric acid used for potentiometric titration

2630

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