Answer Posted / t.tirupathi rao

acetone is react with methanal to form water molecule continue, end point not reached.so pyridine is added to methanol, pyridine is bind the hydrogen molecule in methanol,so do not form the water molecule ,end point reached

If we have 5 strength which is not dose proportinate and excipients also diffrent in each strength then how we can proceed for Force degradation? and excipient are same but not dose propotinate the how FD?

796

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calibrtion procedue of LC-MS

2706

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we are performed SOR for a particular product the limit is -6 to -10.We face particular bathes it is not meeting the specification.we performed diffrent instrument diffrent analyst we are getting diffrent diffrent results.solvent is dimethyl sulfoxide what could be the reasion

1866

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in OSD forms require to use gas chromatography?

830

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in which situation require to change rs specification?

747

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what is mean by peak intigrity?

939

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1.What is the difference between method validation and method verification 2.Which guidelines proposed to method transfer

1842

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As per ICH related substances stability trend limit from initial to shelf life

3244

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how you establish the LOQ?

781

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Why use only methanol,used determinationof moisture content not use other solvents

1400

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How to decide assay range for non pharmacopeial API analysis by HPLC? Could you give me any reference for same e.g Guidelines or Paper publications?

3351

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If we do accuracy at same concentration at which linearity planned,what is the need to do linearity separately?

2296

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sop of a uv visible spectrophotometer double beam elico model

5909

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in hplc chromatogram started from left to right and in uv spectrum started from left to right

941

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What is the requirement for brazil in the analytical method vslidation comparr to ich?

768

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