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Dr Hargobind Khorana
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In horses coat color is dependent upon genes as follows: A_B_ results in bay, aaB_ in black, A_bb in chestnut, aabb in liver. In addition, palimino is derived by Dd with chestnut. A palimono stallion (DdAAbb) is crossed with a palimino mare (DdAAbb). What percent of the offspring will be palimino?
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Consider two linked autosomal genes. The dominant allele C of the first gene causes cataracts of the eye, whereas its recessive allele produces normal eyes. The dominant allele P causes polydactyly (an extra finger) whereas its allele (p) produces a normal number of fingers. A man with cataracts and normal fingers marries a woman with polydactyly and normal eyes. Their son has both polydactyly and cataracts and he marries a woman with neither trait. What is the probability that their first child will have cataracts and polydactyly?
Genetic engineering harms or benefits human societyharms? What obstacles must gene therapy overcome? What instrumentation is required for DNA sequence analysis and how does it work?
A number of plant species have a recessive allele for albinism; homozygous albino (white) individuals are unable to synthesize chlorophyll. If a tobacco plant heterozygous for albinism is allowed to self-pollinate and 500 seeds germinate: a)how many offspring will be the same genotype as the parent? b)how many seedlings would you expect to be white?
In sesame, the one-pod condition (P) is dominant to the three-pod condition (p), and normal leaf (L) is dominant over wrinkled leaf (l). The two characters are inherited independently. Determine the genotypes and phenotypes of the two plants which produce the following progeny: 318 one- pod normal, 98 one-pod wrinkled, 323 three-pod normal and 104 three-pod wrinkled.
A blastomere was removed from an 8-cell human embryo, and its beta-globin gene was amplified by PCR. The beta-globin DNA was treated with an enzyme that cuts on either side of and within the normal allele (producing a small fragment), but not within the sickle cell allele (producing a large fragment). Electrophoresis of the treated DNA from the blastomere demonstrated the presence of both a large and small fragment derived from the beta-globin genes. How should you interpret this test?
Is biotechnology more dangerous to other gene transfer technologies breeding?
In mice colored coat is dominant to albinism. Sniffles, a male mouse with a colored coat is mated to Esmeralda, an alluring albino. The resulting litter of six young all had colored fur. The next time around Esmeralda was mated with Whiskers, who was the same color as Sniffles; some of this litter were white. a)What are the probable genotypes of Sniffles, Esmeralda, and Whiskers? b) If a male of the 1st litterwas mated to a colored female of the 2nd litter, what phenotypic ratio might be expected among the offspring? c)What would be the expected results if a male of the 1st litter was mated to an albino from the 2nd?
The village of Oblong has 400 normally-shaped residents. Transferrin is an iron carrier found in blood, and electrophoretic variation of this protein is determined by an autosomal codominant system. The citizens of Oblong were typed for their transferrin complements. The distribution of transferrin phenotypes was: 100 CC, 100 CD, and 200 DD. What is the frequency of the C allele?
